徐志超

发布时间:2024-03-18文章来源: 浏览次数:

徐志超 教授,博士生导师

E-mail: zcxu@nefu.edu.cn

新葡的京集团35222vip(新逸夫教学楼507


工作经历

2021-05至现在,新葡的京集团35222vip,新葡的京集团35222vip,教授

2016-082021-05,中国医学科学院药用植物研究所,助理研究员,副研究员

2019-092020-09VIB - UGent Center for Plant Systems Biology,访问学者


研究领域

林源活性物质代谢合成及调控;合成生物学;本草基因组学;分子辅助育种;分子鉴定


科研项目(主持)

1. “功效-物质-遗传关联的五味子优良品质形成机制研究,国自然区域重点(联合)

2. 酪氨酸衍生的中药活性成分异源高效生物制造,国家重点研发计划(任务)

3. 濒危药材关黄柏活性成分小檗碱的生物合成机制研究,国自然面上项目

4. 西红花苷生源途径解析及合成生物学研究,国自然面上项目

5. 中药多组学方法创新及新品种选育研究,国家重点研发计划(课题)

6. 丹参酮生物合成关键酶短链脱氢酶编码基因的克隆和功能鉴定,国自然青年基金


代表性论文(第一及通讯,含共同,IF2023

1. Convergent evolution of berberine biosynthesis, Science Advances, 2024, 10, eads3596 (IF=11.7)

2. Lineage-specific CYP80 expansion and benzylisoquinoline alkaloid diversity in early-diverging eudicots. Advanced Science, 2024, 2309990 (IF=14.3)

3. Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery. Nature Communications, 2024, 15: 1537 (IF=14.7)

4. Structural diversity, evolutionary origin, and metabolic engineering of plant specialized benzylisoquinoline alkaloids. Natural Product Reports, 2024, 41, 1787-1810 (IF=10.2)

5. Lonicera caerulea genome reveals molecular mechanisms of freezing tolerance and anthocyanin biosynthesis, Journal of Advanced Research, 2024, 10.1016/j.jare.2024.12.038. (IF=11.4)

6. Crocus genome reveals the evolutionary origin of crocin biosynthesis. Acta Pharmaceutica Sinica B, 2024, 14(4):1878-1891. (IF=14.7)

7. Heterologous biosynthesis of saponin adjuvants from Quillaja saponaria: A symbolic achievement in metabolic engineering. Acta Pharmaceutica Sinica B, 2024, 14(12):5518-5520. (IF=14.7)

8. Functional evolution and diversification of the CYP82D subfamily members shape flavonoid diversification in the genus Scutellaria. Plant Communications, 2024, 10.1016/j.xplc.2024.101134. (IF=9.4)

9. Characterization of the horse chestnut genome reveals the evolution of aescin and aesculin biosynthesis. Nature Communications, 2023, 14: 6470 (IF=14.7) Highlight

10. Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia. Nature Communications, 2023, 14: 4696 (IF=14.7)

11. Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis, Horticulture Research, 2023, uhad150. (IF=7.6) Cover story

12. Herbgenomics: Decipher molecular genetics of medicinal plants, Innovation, 2022, 3(6): 100322. (IF=33.2)

13. Comparative genomics reveal the convergent evolution of CYP82D and CYP706X members related to flavone biosynthesis in Lamiaceae and Asteraceae. Plant Journal, 2022, 109(5):1305-1318 (IF=6.2)

14. The genome of Corydalis reveals the evolution of benzylisoquinoline alkaloid biosynthesis in Ranunculales. Plant Journal, 2022, 111(1):217-230 (IF=6.2)

15. The honeysuckle genome provides insight into the molecular mechanism of carotenoid metabolism underlying dynamic flower coloration. New Phytologist, 2020, 227(3):930-943. (IF=8.3)

16. Comparative Genome Analysis of Scutellaria baicalensis and Scutellaria barbata Reveals the Evolution of Active Flavonoid Biosynthesis. Genomics Proteomics and Bioinformatics, 2020, 18: 230-240. (IF= 11.5)

17. Trends in Herbgenomics. SCIENCE CHINA Life Sciences, 2019, 62(3): 288-308. (IF=8)

18. Genome analysis of the ancient tracheophyte Selaginella tamariscina reveals evolutionary features relevant to the acquisition of desiccation tolerance. Molecular Plant, 2018, 11: 983-994. (IF=17.1) SPOTLIGHT, ESI Highly Cited Paper

19. The 2-oxoglutarate-dependent dioxygenase superfamily participates in tanshinone production of Salvia miltiorrhiza. Journal of Experimental Botany, 2017, 68 (9): 2299-2308. (IF= 5.6)

20. Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis. Plant Journal, 2015, 82:951-961. (IF=6.2) ESI Highly Cited Paper


出版著作及教材

1.《药用植物分子遗传学》科学出版社十四五本科规划教材 2024(主编)

2.《药用植物分子遗传学》科学出版社 2022

3.《本草基因组学-中药组学的发展与未来》 科学出版社 2016

4.《本草基因组学》全国高等医药院校规划教材 科学出版社 2018

5.《药用植物品质生物学》科学出版社 2019

6. “The Genome of Salvia miltiorrhiza” ofThe Salvia miltiorrhiza GenomeSpringer 2019


奖励

1. 中草药国际通用DNA条形码鉴定体系,世界中医药学会联合会,中医药国际贡献奖科技进步奖,一等奖,2018

2. 黑龙江省高等教育和职业教育教学成果奖,一等奖,2022

3. 濒危重楼属植物资源种质创新与产业化应用,中国产学研合作创新与促进奖,产学研合作创新成果奖二等奖,2024


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